ASSIGN Score – prioritising prevention of cardiovascular disease

FAQs

Who is this information for?

This information is for anyone who wants a simple introduction to the ASSIGN score and how it is used. More advanced information is also available on this website.

What is the ASSIGN score?

The ASSIGN score estimates a person's risk of developing cardiovascular disease. It is used to identify who is at high risk of having a heart attack or stroke. He or she can then be given special attention (see below).

What is cardiovascular disease?

Cardiovascular disease affects the heart or blood vessels. Among others it includes five serious conditions which share the same causes:

Coronary heart disease and stroke cause two out of every five deaths in Scotland and elsewhere. They also cause a great deal of illness in middle and old age.

Everyone is at risk of getting cardiovascular disease, but some people are more at risk than others.

How does the ASSIGN score work?

ASSIGN combines those factors which identify people who are at increased risk of cardiovascular disease to produce an overall score, the ASSIGN score. These risk factors are:

The ASSIGN score combines all the risk factors, and gives a score between 1 and 99. The higher the score, the higher the risk of cardiovascular disease.

A score of 20 or more is considered to be high, and is used to identify those people in greatest need of advice and treatment to reduce their risk.

What if my risk factors have changed in the last few years?

The ASSIGN score is designed first to identify high risk for people who have never had an assessment of their cardiovascular risk, and who are therefore unlikely to be on cardiovascular medication. It can be used to check progress in the latter, but that is not its main purpose. However, the question will arise as to what to do when risk factors are changing:

Smoking The added risk from smoking does not disappear immediately when somebody stops, but there is discussion as to how rapidly this happens. ASSIGN uses number of cigarettes a day as a measure of the smoking dose. A simple rule is to divide the number of cigarettes regularly smoked before quitting by the number of years plus one since quitting. So after one year the previous number of cigarettes can be halved, and after two years divided in three. After five years the person can be treated as not smoking cigarettes.

A cigarette smoker needs to stop completely as ‘cutting back’ usually means inhaling as much as before, so the dose is as before. This applies also to cigarette smokers converting to pipe or cigar smoking.

(The study used for ASSIGN had insufficient numbers to quantify risk in primary cigar or pipe smokers but they do have increased risk in other studies. Rather than classifying other tobacco smokers as equivalent to non-smokers with zero consumption of cigarettes, it would be reasonable to record the number of times they smoke per day as the equivalent cigarette dose, or double it for large cigars/ pipefuls.)

Cholesterol When blood cholesterol is lowered the cardiovascular risk comes down fairly rapidly. Patients put on cholesterol lowering medication should have had a cardiovascular risk assessment when it was started. If medication changes status from “high-risk” to “non high-risk” that is not a reason for stopping medication. Occasionally historical data on blood cholesterol and other risk factors might be used to look back and review whether medication was justified in the first place.

Blood pressure The modern approach to blood pressure treatment and control should involve a full cardiovascular risk assessment. When blood pressure is lowered, the global cardiovascular risk does not come down as rapidly as for other risk factors. So risk is intermediate between the historical and current values shown by the ASSIGN score. Those on antihypertensive medication are already in medical care and should be considered for treatments additional to blood pressure lowering. The ASSIGN score might be used for this. However, most patients should already be following a treatment plan or protocol targetting their cardiovascular risk alongside their blood pressure.

What does the ASSIGN number mean?

The ASSIGN score number is the estimated risk percent of getting cardiovascular disease over ten years. It is based on what happened to Scots men and women in the 1980s and 1990s (when risk factors were not being systematically treated). So ASSIGN 20 means a 20% risk, or one chance in five. The actual risk is almost certainly now less than that. What matters more is what somebody's score is in relation to other people's scores, and therefore how badly they need prevention now to lower their risk.

A high score (20 or more) does not mean you will definitely have a heart attack or stroke. It does mean that your chances are definitely worse than someone with a score below 20.

An ASSIGN score under 20 does not mean that you will never have a heart attack or stroke, only that you have a lower priority for preventive treatment than someone with a score of 20 and above.

The ASSIGN score is not used for people who have already been diagnosed with cardiovascular disease and are receiving treatment. If you have been diagnosed with one or more of the cardiovascular diseases in the list above, but are not receiving treatment, ask your GP about it.

What happens if I have a high ASSIGN score?

In Scotland you should be offered advice, support and treatment. That support may include being invited to join groups to help you with your diet, to stop smoking or to take exercise suitable for your age and health. Treatment would probably include medication to help reduce the chances of developing cardiovascular disease. These medicines could include:

These medicines are known to reduce the risk of developing cardiovascular disease.

If your ASSIGN score is not as high as 20, you may still be given (or should find) advice about things you can do to improve your own health and lower your risk such as:

To find out more go to http://www.takelifeon.co.uk (external link)

What is the ASSIGN score based on?

The ASSIGN score is based on research carried out with 13,000 Scottish men and women in the 1980s and 1990s. These people had their risk factors measured and were followed for 10 years or more to see who developed cardiovascular disease.

Find out more about the SHHEC study (Scottish Heart Health Extended Cohort) used in the ASSIGN score.

Why is Scotland using the ASSIGN score when other cardiovascular scores are used elsewhere?

The most commonly used cardiovascular risk score worldwide is the Framingham score, developed in the USA. It is a good score that works well. There is also a European SCORE score. In Scotland much cardiovascular disease is associated with social deprivation. This is not fully explained by the risk factors included in the Framingham score. So the Framingham score does not target the socially deprived for treatment as much as they deserve compared with other social groups. The ASSIGN score is the first to include social deprivation and to deal with this social inequality. It also includes family history. For these reasons it is recommended for use in Scotland as against other scores.

How does ASSIGN fit into preventive policies in Scotland and elsewhere?

ASSIGN was developed within, and should be implemented within, a programme for both primary and secondary prevention of CVD. It was launched with SIGN Guideline 97 in February 2007. The Scottish Government is committed to reducing health inequalities through Equally Well and therefore recommends ASSIGN as the preferred cardiovascular risk score for primary prevention, and is hosting its updated website. General practitioners in Scotland are not routinely offering cardiovascular risk assessment and scoring to all their patients; to do so implies increasing workloads, more in socially deprived areas. This is under evaluation. ASSIGN is being incorporated into GP database systems. Testing of ASSIGN is taking place within the Scottish Government programme of targeted high risk primary prevention, initially established in the Keep Well initiative for people aged 45-64 in the 15% most socially deprived areas in Scotland. Evaluation and estimation of the impact of ASSIGN in practices across Scotland will inform decisions regarding target populations for assessment (age and locality), and treatment thresholds, which could be progressive, and help thereby to optimise ASSIGN’s potential for reducing inequalities in CVD when nationally implemented.

ASSIGN could be used outside Scotland with adjustment for local indices of social deprivation, where available. Unlike conventional risk factors, these indices are not standardised internationally. Treatment thresholds would again need to be calibrated to the estimated workload. The ASSIGN website (www.assign-score.com) has generated heavy usage internationally, despite the need of users elsewhere to substitute for the SIMD score.

Can I measure my own ASSIGN score?

If you would like to measure your ASSIGN score on this website you can enter your risk factors. If you don’t know one or two of your risk factors you can use the average values for the Scottish population – but this will make the result less specific to you. If your score is near to or over 20, and you have not already spoken to your GP about cardiovascular disease, you should go to your GP for advice about further testing, self-help, other support or treatment.

Measuring your score is not a substitute for self-help or active treatment to lower risk. It is just a first step in helping you in prioritising prevention of cardiovascular disease. The ASSIGN score is best measured in a setting where the follow-through of advice and medication and follow-up are available from health professionals.

Where can I find out more?

If you are worried about your health or your risk of heart attack and stroke, you can call (in Britain) NHS 24 on 08454 24 24 24 or speak to your GP.

Further information for professionals and other people who would like to know more is available on this website and in the listed publications.

Estimate the risk

Estimate the risk of developing cardiovascular disease over ten years using the ASSIGN score, by entering personal details and clicking on calculate.

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